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'Pro-choice Community' Should Find New 'Way Of Talking About Reproductive Freedom,' Opinion Piece Says
"Most of the push-back" from antiabortion-rights advocates to a recent e-mail message from author Judy Blume on behalf of Planned Parenthood -- which asked mailing list subscribers for donations -- was generated by an article in the antiabortion-rights publication LifeNews, columnist Meghan Daum writes in a Los Angeles Times opinion piece. The article put a "heavy, misrepresentative spin" on Blume"s message, which urged donors to "do all [they] can to support" the increasing number of women turning to Planned Parenthood centers for health care during the economic downturn.The LifeNews article said, "Blume notes how more women are seeking abortions from Planned Parenthood because of the difficult economy, and she urges readers of the e-mail to use that as a reason to support the abortion business." According to Daum, "this is just the kind of thing that makes abortion-rights advocates apoplectic," noting that abortion-rights advocates "fired-back" in the "blogosphere ... imparting the statistic about abortion making up only 3% of Planned Parenthood"s services and pointing out that many of the women being yelled at by picketers in clinic parking lots aren"t even pregnant but, rather, trying to avoid getting pregnant." Daum continues that the organization, much like Blume, "occupies a clear position on the post-Roe cultural map," adding, "Generally speaking, if you"re on board with abortion rights, you"re on board with Planned Parenthood." In addition, if you are against abortion rights, the "organization is the headquarters of Godlessness," she adds. Daum writes that it is not difficult to see why Planned Parenthood enlisted Blume -- an "icon of 1970s-era feminism and its efforts on behalf of sex education and women"s health" -- because she conjures "nostalgia for the early days of the fight that makes pro-choicers want to keep fighting today."Daum writes that as she watched this "saga unfold in [her] inbox," she was "struck by a troubling question. Even though Blume may not be associated with abortion in and of itself … is there something about her persona that signals a lack of dispassion about its ramifications? Is she reminding people of a time when, in the relief of Roe being decided, there was a cultural perception that abortion was a simple procedure that needn"t come with attendant emotional baggage?"Daum adds that there is "no denying that the language and overall tone around abortion has changed. Despite what many pro-life groups seem to think, most abortion-rights advocates prefer "safe, legal and rare" to "no big deal."" According to Daum, President Obama, "pro-choice though he is, is hardly strident -- and even a little evasive -- on the issue." She adds that Obama favors language about reducing the need for abortions and "finding common ground with the other side." Daum notes that the pop cultural arena "has become downright allergic to the issue" of abortion, with a recent movie coining the term "shmashmortion" because the characters "can"t even get the word out." Daum adds that although Blume "was undoubtedly effective" at bringing in funding for Planned Parenthood, perhaps what might have been "even more radical is if the pro-choice community could find a way of talking about reproductive freedom that neither reverts to the perceived casualness of the 1970s nor panders to the "shmashmortion" dialect of today. "Safe, legal and rare" comes close. But "safe, legal, rare and a big deal" might be even better" (Daum, Los Angeles Times, 5/14).

HITSP Begins Harmonization Process For Use Of Electronic Health Records In Clinical Research
The Healthcare Information Technology Standards Panel (HITSP), a cooperative partnership between the public and private sectors that works to ensure the interoperability of electronic health records (EHRs) in the United States, has begun work to identify global standards to support "core research data element exchange," specifically, a common set of information that can readily be exchanged between EHRs and clinical research systems.
News of the day
Blogs Comment On 'Common Ground' Bill, Abortion Coverage In Health Reform Legislation, Other Topics
The following summarizes selected women"s health-related blog entries.~ "Democratic Bill Could Be a Preview of Obama"s Abortion Plan," Dan Gilgoff, U.S. News & World Report"s "God and Country": A recently introduced bill aimed at reducing the need for abortion is "big news because moderate to liberal faith-based advocates are urging the White House to adopt the bill ... as the core of its forthcoming "common ground" plan on abortion and reproductive health," Gilgoff writes. Some conservative religious groups, including the Southern Baptist Convention and the U.S. Conference of Catholic Bishops, "have warned the White House" that the bill is a "deal breaker" for them because of its support for comprehensive sex education and contraception, he writes. The White House "has refused to say which way it"s leaning," Gilgoff writes, adding the Obama administration could "buck" the groups that support the bill and "get behind" the Pregnant Women Support Act, "which is generally considered more robust on reducing demand for abortions and which leaves out contraceptive funding." However, he concludes, "that would be a pretty big surprise" (Gilgoff, "God and Country," U.S. News & World Report, 7/23).~ "New Report: Abortion Providers = American Human Rights Defenders, Now Under Increasing Attack," Jodi Jacobson, RH Reality Check: A new Center for Reproductive Rights report "calls on both the federal and state governments to address the growing threats against and stigmatization and abuse of abortion providers throughout the United States," Jacobson writes. The report "focuses on a key obstacle to the realization of women"s reproductive rights ... and recognizes their work as human rights defenders," she writes, adding that the U.S. has "historically been a leader both in creating and in encouraging accountability to human rights principles throughout the world." However, "[a]ccess to reproductive health care generally and abortion care specifically are basic human rights largely ignored within the context of U.S. domestic politics," Jacobson writes, noting that abortion access in the U.S. "has been increasingly limited due to the range of obstacles created through anti-choice advocacy." The report highlights several "types of rights violations [that] are most pervasive in limiting women"s choices and the rights of abortion providers," including "intimidation and harassment," "stigma" and "legal restrictions." The report makes a "series of recommendations for change at the state and local level for changes in policy and in law enforcement practices, as well as for the federal government, medical community and non-governmental organizations," Jacobson concludes, adding that the report "makes a special plea for the United Nations Special Rapporteur to document violations of women"s human rights in the United States" (Jacobson, RH Reality Check, 7/22).~ "Sixteen Governors Call on Congress To Include Medicaid Family Planning State Option in Health Reform," Jodi Jacobson, RH Reality Check: "Sixteen governors have written a letter to both Senate and House Leadership "expressing strong support for the Medicaid Family Planning State Option,"" which is included in President Obama"s fiscal year 2010 budget proposal, Jacobson writes. The governors wrote, "Many of our states have created family planning expansion programs, though we have done so with great difficulty," adding, "Since the early 1990s, 27 states have been granted federal waivers to expand their Medicaid family planning coverage. These demonstration projects have been unqualified successes, providing care to millions of women while saving states [millions] of dollars." Jacobson continues, "The current Medicaid waiver process, however, "puts unnecessary roadblocks in the way of our efforts to maintain and expand coverage for family planning services,"" according to the governors. She adds, "Passing this law as part of health care reform "would give us the needed flexibility to quickly and efficiently expand cove
Medical Devices

Will IVF Work For A Particular Patient? The Answer May Be Found In Her Blood

For the first time, researchers have been able to identify genetic predictors of the potential success or failure of IVF treatment in blood. Dr. Cathy Allen, from the Rotunda Hospital, Dublin, Ireland, told the 25th annual conference of the European Society of Human Reproduction and Embryology today (Wednesday 1 July) that her research would help understand why IVF works for some patients but not for others. Previous work in this area has looked at gene profiles in such tissues as the uterine lining, but Dr. Allen and her team chose to examine the gene expression patterns in RNA extracted from peripheral (circulating) blood, an easily accessible biological sample. Blood samples were taken at eight different stages during the period around conception and the early stages of the IVF cycle. Five of these samples came from women who achieved clinical pregnancies, three from those who had implantation failure, and three from subfertile women who conceived spontaneously. Analysis showed that 128 genes showed a more than two-fold difference in expression in early clinical pregnancy compared with a non-pregnant state. The molecular pathways that were most over-represented in this expression were concerned with angiogenesis (the growth of new blood vessels), endothelin signalling (blood vessel constriction), inflammation, oxidative stress (damage to cell structures), vascular endothelial growth factor (signalling processes in blood vessel growth), and pyruvate metabolism (the supply of energy to cells). "All these processes are important in the achievement and maintenance of pregnancy," said Dr. Allen. "We found that the gene expression profiles in blood of patients at the time of pituitary down-regulation showed interesting patterns of gene clustering. Over 200 genes were differentially expressed in patients who went on to achieve an IVF pregnancy compared with those who did not," she said. The researchers found that the peripheral blood gene expression "signature" (also known as the transcriptome) before IVF was predictive of IVF outcome. This finding demonstrates the power of high-dimensional technology in biomarker discovery, and highlights the potential for developing clinically useful tools, they say. One of the most difficult decisions for patients who have had unsuccessful IVF treatments is whether they should undergo further attempts at IVF, or if there are ways to optimise chances of success. The researchers hope that the results generated by this work will lead to the development of a test to aid in IVF decision-making. They say that their work will help to identity biomarkers that can identify events occurring at implantation, the maintenance of pregnancy and successful or unsuccessful pregnancy outcome. "IVF technology has advanced tremendously over the past three decades, yet success after IVF remains an unpredictable outcome," said Dr. Allen. "Our work will help understand whether the implantation of embryos is influenced by the constantly changing expression of human genes." Previous studies in the field of gene-expression have focused on single genes as opposed to genome-wide screening of all the human genes with high density DNA microarrays, as used by Dr. Allen and her team. The advent of tools like microarrays that can simultaneously probe for up to 29,000 genes has radically changed scientific approaches to this type of research. "It"s like looking at how a team of players perform together rather than focusing on the individual players," said Dr. Allen. "We intend to look further at the most significant genes we have identified as being important in this field in order to be able to understand their exact biological role in reproductive function. We hope that our work will lead to the development of a clinically useful tool to help doctors counsel their patients in the difficult decision-making involved in IVF," she said. ESHRE


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