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MDC Researchers Unravel Key Mechanism In Pathogenesis Of Osteoporosis
Osteoporosis, or bone loss, is a disease that is most common in the elderly population, affecting women more often than men. Until now, it was not clear exactly how the disease develops. Researchers of the Max Delbr̿ck Center for Molecular Medicine (MDC) Berlin-Buch, Germany, have now elucidated a molecular mechanism which regulates the equilibrium between bone formation and bone resorption. Dr. Jeske J. Smink, Dr. Val̩rie B̩gay, and Professor Achim Leutz were able to show that two different forms of a gene switch - a short isoform and a long isoform - determine this process. The MDC researchers hope these findings will lead to new therapies for this bone disease. (EMBO Journal)*.

The Royal Society For Public Health Announces It Will Be Delivering Training Sessions
The Royal Society for Public Health (RSPH) announces it will be delivering training sessions for the RSPH Level 1 Health Awareness and the RSPH Level 2 Understanding Health Improvement awards.
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What Is Gonorrhea? What Causes Gonorrhea?
Gonorrhea (from Late Latin gonorrhoia where gonos means "seed" and rhoe means "flow") is a sexually transmitted bacterial infection that tends to attack the mucous membranes of the body. It is the second most common sexually transmitted disease in the U.S.; the first being Chlamydia. The bacteria reside in the warm and moist body cavities of both men and women and are highly contagious. Gonorrhea is the most common cause of female infertility and is also known as "the clap" or "the drip". Only a fraction of women infected with the disease show any symptoms, leaving them unaware of their condition. If left untreated, gonorrhea patients can develop pelvic inflammatory disease or PID (women), or an inflammation of the epididymis, prostate gland, or urethral structure (men), all of which are far more difficult to treat.
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Statins May Be Linked To Muscle Damage

A recent study published in the Canadian Medical Association Journal (CMAJ) reports that patients taking statins with associated muscle complaints may have structural muscle damage. Because of their important role in reducing the risk of cardiovascular disease, statins are one of the most widely prescribed medications worldwide. However, many patients on statins develop muscle weakness and pain. In a number of cases, muscle biopsies confirm underlying structural injury, even in patients who do not show elevated levels of circulating creatine phosphokinase. The study was the work of researchers from the University of Bern, Switzerland and the Tufts-New England Medical Center in Boston, Massachusetts. They evaluated muscle biopsies from eighty three patients. Twenty of them had never taken statins. Results showed significant muscle injury in patients who had taken statins, including several who had discontinued medication before the biopsy. Dr. Annette Draeger from the University of Bern and coauthors explain: "Although in clinical practice, the majority of patients with muscle symptoms improve rapidly after cessation of therapy, our findings support that a subgroup of patients appears to be more susceptible to statin-associated myotoxicity, suffering persistent structural injury." The researchers call for further evaluation of alternative treatment strategies for patients with significant muscle symptoms. "Association between statin-associated myopathy and skeletal muscle damage" Markus G. Mohaupt, MD, Richard H. Karas, MD PhD, Eduard B. Babiychuk, PhD, VerÓ³nica Sanchez-Freire, Katia Monastyrskaya, PhD, Lakshmanan Iyer, PhD, Hans Hoppeler, MD, Fabio Breil and Annette Draeger, MD CMAJ ò€¢ July 7, 2009; 181 (1-2). doi:10.1503/cmaj.081785. cmaj Written by Stephanie Brunner (B.A.) Copyright: Medical News Today Not to be reproduced without permission of Medical News Today


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