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New Strategy Proposed For Designing Antibody-Based HIV Vaccine
Most vaccines that protect against viruses generate infection-fighting proteins called antibodies that either block infection or help eliminate the virus before it can cause disease. Attempts to create a vaccine that induces antibodies that prevent HIV infection or disease, however, have so far been unsuccessful. But several recent studies suggest promising new research directions for the development of an antibody-based HIV vaccine, according to John R. Mascola, M.D., deputy director of the Vaccine Research Center at the National Institute of Allergy and Infectious Diseases of the National Institutes of Health, and colleagues.

Needs Of Bottle Feeding Mums Neglected
The needs of mothers who bottle feed are being neglected, potentially risking the health of their babies, suggests research published ahead of print in the Archives of Disease in Childhood.
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The Improvement Foundation - Helping Tackle The Decline In Cervical Cancer Screening Uptake
Cervical Cancer Awareness Week 8-14 June 2009 is a key time to remind women that it is of huge importance that they attend their screening appointment when asked. The Improvement Foundation (IF) aim to help tackle the decline in screening uptake by addressing levels of complacency among clinicians and the public through their national Cervical Screening Improvement Programme.
Sexual Health

New Insights Into The Mystery Of "High Risk Platelets" From Diabetic Donors

Amid emerging concerns that blood platelets donated for transfusion by individuals with Type 2 diabetes may be unsafe, scientists are reporting the first detailed identification and analysis of a group of abnormal proteins in platelets from diabetic donors. The study could lead to screening tests to detect and monitor these so-called "high risk platelets," the researchers say. Their study is scheduled for the June 5 issue of ACS" Journal of Proteome Research, a monthly publication. About 18 million people in the United States have Type 2 diabetes, and the disease is spreading with the epidemic of obesity. David Springer and colleagues point out in the new study that thousands of patients receive potentially lifesaving transfusions of platelets each year to treat bleeding from trauma and for a wide range of medical conditions. Scientists have known that abnormal platelets in the blood of diabetics may predispose these individuals to heart disease. It led to concern that platelets from these individuals stored for transfusion may be less effective and even unsafe. However, scientists know little about how diabetic platelets differ from those of healthy people. The new study identified 122 proteins that differed in the platelets of individuals with diabetes compared to the platelets of non-diabetics. They also found that freshly collected platelets from diabetics show almost as many abnormal changes (more than 100) in protein content as healthy donor platelets stored for up to 5 days. These findings could lead to new tests for detecting and monitoring abnormal platelets to improve the outcome of blood transfusions from both diabetic and healthy individuals, the researchers say. American Chemical Society


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