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Human Term Placenta A New Abundant Of Hematopoietic Cells
Investigators at Children"s Hospital Oakland Research Institute, Oakland, California found a way to obtain large numbers of hematopoietic stem cell from human term placenta. The results, which appear in the July 2009 issue of Experimental Biology and Medicine, describe detailed report on quantification, characterization, engraftment capacity, and most importantly, practical way to obtain hematopoietic stem cells from placenta in numbers that are several-fold higher than could be obtained from cord blood.

CDC Introduces New Website To Help Employers Combat Obesity And Reduce Health-Related Costs
The Centers for Disease Control and Prevention (CDC) today unveiled LEANWorks!, a Website designed to help businesses address obesity. LEAN stands for Leading Employees to Activity and Nutrition. The new Website was announced at a National Business Group on Health meeting in Washington, D.C.
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Enzon Commences Phase II Trial Of PEG-SN38
Enzon Pharmaceuticals, Inc. (Nasdaq: ENZN) announced that it has opened its first Phase II trial for PEG-SN38 (EZN-2208), its novel proprietary cancer compound. The trial is open at multiple centers throughout the United States for patients diagnosed with metastatic colon cancer.
Mental Health

Fallopian Tubes Offer New Stem Cell

Human tissues normally discarded after surgical procedures could be a rich additional of stem cells for regenerative medicine. New research from BioMed Central"s open access Journal of Translational Medicine shows for the first time that human fallopian tubes are abundant in mesenchymal stem cells which have the potential of becoming a variety of cell types. It has previously been shown that mesenchymal stem cells obtained from umbilical cords, dental pulp and adipose tissue, which are all biological discards, are able to differentiate into muscle, fat, bone and cartilage cell lineages; therefore, the search for s to obtain multipotent stem cells from discarded tissues and without ethical problems is of great interest. Tatiana Jazedje, and the research team from Human Genome Research Centre at the University of Sç£o Paulo, directed by Mayana Zatz, with the collaboration of medical doctors from the reproductive area, set out to isolate and assess the differentiation potential of mesenchymal stem cells from discarded human fallopian tubes. In the study, human fallopian tubes were obtained from hysterectomy and other gynecological procedures from fertile women in their reproductive years (range 35-53 years) who had not undergone hormonal treatment for at least three months prior to surgery. The Brazilian team found that human fallopian tube mesenchymal stem cells could be easily isolated and expanded in vitro, and are able to differentiate into muscle, fat, cartilage and bone cell lines. The cells" chromosome complement showed no abnormalities, suggesting chromosomal stability. Jazedje comments, "In addition to providing an additional potential for regenerative medicine, these findings might contribute to reproductive science as a whole." Jazedje concludes, "Moreover, the use of human tissue fragments that are usually discarded in surgical procedures does not pose ethical problems." Notes: Human fallopian tube: a new of multipotent adult mesenchymal stem cells discarded in surgical procedures Tatiana Jazedje, Paulo M Perin, Carlos E Czeresnia, Mariangela Maluf, Silvio Halpern, Mariane Secco, Daniela F Bueno, Natassia M Vieira, Eder Zucconi and Mayana Zatz Journal of Translational Medicine (in press) Article available at journal website. All articles are available free of charge, according to BioMed Central"s open access policy. Journal of Translational Medicine is an open access journal publishing articles focusing on information derived from human experimentation so as to optimise the communication between basic and clinical science. Charlotte Webber BioMed Central


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