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Swine Flu: New 3-D Structural Model Of Critical H1N1 Protein Developed
In just two weeks from the time the first patient virus samples were made available, Singapore scientists report an evolutionary analysis of a critical protein produced by the 2009 H1N1 influenza A virus strain.

CMS Proposes Payment, Policy Changes For Physicians Services To Medicare Beneficiaries In 2010
The Centers for Medicare & Medicaid Services (CMS) announced today proposed changes to policies and payment rates for services to be furnished during calendar year (CY 2010) by over 1 million physicians and nonphysician practitioners who are paid under the Medicare Physician Fee Schedule (MPFS). The MPFS sets payment rates for more than 7,000 types of services in physician offices, hospitals, and other settings.
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Members Announced For The MHRA's Agency Board
The Medicines and Healthcare products Regulatory Agency (MHRA) and the Appointments Commission are pleased to announce two new appointments and two reappointments of non-executive directors to the Agency Board.
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Emerging Health Care Crisis In The Developing World: Gram-Negative Rods Discovered In Two Philippine Neonatal Intensive Care Units

Researchers at Boston University School of Medicine (BUSM) have found a high frequency of multidrug-resistant Gram-negative rods (GNRs) in two of the largest neonatal intensive care units (NICUs) in the city of Manila, Philippines. Improved infection control methods could reduce the vast number of hospital acquired neonatal infections. The BUSM study appears online in the journal Infection Control and Hospital Epidemiology. According to researchers, hospital acquired infections have emerged as a significant health problem in developing areas. Neonatal mortality accounts for more than one third of all global child deaths each year. Sepsis is a leading cause of death within the first month of life and is often acquired through unhygienic care practices in healthcare facilities, which frequently have limited emphasis placed on standard infection control measures. Over a 10-month period, BUSM researchers conducted studies for colonization and bloodstream infections with gentamicin or third generation cephalosporin-resistant GNR among all NICU infants weekly and then on the day of discharge. Researchers found a total of 1,997 resistant GNRs colonizing 1,831 neonates. Results also showed that 376 newborns became bacteremic with a total of 437 GNRs. The most common GNR species identified were Klebsiella, Acinetobacter, Pseudomonas aeruginosa and Enterobacter. A high proportion of colonization and bacteremia at the two NICUs was with non-intestinal GNRs. Factors significantly associated with increased risk of bacteremia were mechanical ventilation and prematurity. Additionally, colonization with a resistant GNR was an independent risk factor for bacteremia. "Colonization with a resistant GNR was an independent risk factor for sepsis," said senior author, Davidson Hamer, MD, associate professor of international health and medicine at Boston University School of Public Health, and director of Boston Medical Center"s Travel Clinic. "The unusually high intensity of colonization pressure and disease with multidrug-resistant GNRs at these two NICUs constitutes an emerging health care crisis in the developing world." This study was funded by the United States Agency for International Development, the Health Res and Services Administration and the National Institute of Allergy and Infectious Diseases. These organizations had no role in the design and conduct of the study, the collection, management, analysis and interpretation of the data, or the preparation, review and approval of the manuscript. Michelle Roberts Boston University Medical Center


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