Popular Articles

New Method For Detecting Nitroxyl Will Boost Cardiac Drug Research
Wake Forest University scientists have developed a new research tool in the pursuit of heart medications based on the compound nitroxyl by identifying unique chemical markers for its presence in biological systems.

AVEO's Tivozanib Demonstrates Anti-Tumor Activity In Engineered Lung Tumors Exhibiting Treatment Resistant Mutations
AVEO Pharmaceuticals, Inc., a biopharmaceutical company leveraging breakthrough discoveries in cancer biology to discover, develop and commercialize targeted oncology therapies, today announced data which demonstrates that tivozanib (AV-951) - the company"s oral, triple VEGF receptor inhibitor - exhibits potent anti-angiogenic and anti-tumor activity in AVEO"s proprietary in vivo lung cancer models. Specifically, treatment with tivozanib resulted in complete tumor growth inhibition or tumor regression (shrinkage) in lung tumors driven by EGFR or KRAS mutations, which are especially difficult to treat. These data are being presented today at the 13th World Conference on Lung Cancer (WCLC) in San Francisco, abstract number PD10.1.5.
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AMP Urges Inclusion Of Molecular Diagnostic Tests In Comparative Effectiveness Research
The Association for Molecular Pathology (AMP) recently released the text of a comment letter it has provided to the Federal Coordinating Council for Comparative Effectiveness Research (CER) in which AMP sets forth its recommendations for priority areas on which to focus CER activities.
Health Insurance

AARP Ramps Up Effort To Close Medicare Doughnut Hole One In Five Fall Into The Gap, But Few Climb Out

WASHINGTON-AARP"s Health Action Now campaign turns its attention this week to the growing problem of prescription drug costs and reducing the gap in prescription drug coverage for people in Medicare. Closing the Part D doughnut hole could save people in the program thousands of dollars in drug costs and keep them healthier by ensuring they can afford their medications. The Association is pressing lawmakers to lower individuals" drug costs as a part of health reform, including closing the doughnut hole-which forces more than 3 million people in Medicare to pay their full drug costs each year-and increasing the availability of generic drugs, particularly generic versions of costly biologics. "Prescription drug coverage has literally been a life-saver for people in Medicare, but the widening doughnut hole is still leaving too many Americans on their own to face skyrocketing drug costs," said AARP Executive Vice President Nancy LeaMond. "We know that higher costs lead people to skip doses or give up their prescriptions entirely, putting their health in jeopardy and driving up long-term costs." AARP is working with leaders on Capitol Hill to close the doughnut hole, which is predicted to top $6,000 by 2016. Today, 3.4 million people fall into the gap each year, while only 15 percent of those are able to get out and receive catastrophic coverage. AARP is also fighting to bring more generic drugs to market, particularly generic versions of costly biologic drugs used to treat diseases like cancer and multiple sclerosis. Unlike traditional chemical drugs, biologics are created from living organisms and have no FDA approval process for generic versions. Without generic competition, biologic makers are free to charge thousands of dollars per month, even for drugs that have been on the market for many years. LeaMond added: "Since the 1980s, safe, affordable generic drugs have helped Americans save billions of dollars on their health care bills. With biologics now making up a large and growing share of the market, it"s time to bring those same savings to people taking these breakthrough drugs while protecting medical innovation." AARP has endorsed the "Promoting Innovation and Access to Life-Saving Medicine Act" (H.R. 1427/S. 726), which would create an FDA approval process-similar to that for traditional prescription drugs-for generic biologic drugs. In addition, AARP is working to help the four million low-income Americans who are eligible for the Medicare Part D Low-Income Subsidy, which greatly reduces a person"s drug costs and has no gap in coverage. The Association is fighting to increase access to the benefit by raising and ultimately eliminating the asset limit, expanding eligibility, standardizing eligibility rules, and raising awareness about the program. AARP


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